“This study seeks to demonstrate the feasibility and preliminary efficacy of a new telehealth model of care for cancer-related fatigue which could influence future CRF interventions and models of care for cancer survivors.”
Cancer related fatigue (CRF) is a debilitating adverse effect of cancer and its treatment reported by cancer survivors. Physical activity, psychological interventions and management of concurrent symptoms have been shown to be effective in alleviating CRF. There is no systematic model of care in the acute cancer care setting that specifically targets CRF.
This pilot randomised controlled trial (RCT) will determine the feasibility of a telehealth CRF clinic intervention (T-CRF) to implement evidence-based strategies and assess the impact of the intervention on CRF and other clinical factors in comparison to usual care.
The T-CRF pilot trial has a primary objective to determine the feasibility of the intervention (evidenced by identification of recruitment methods; recruitment rate and uptake; attrition; adherence; fidelity; apathy; and intervention functionality, acceptability and satisfaction) and secondarily to determine the clinical efficacy (looking at cancer survivor fatigue, symptom burden, level of physical activity, productivity loss, hospital resource utilisation and carer’s fatigue and productivity loss).
From Flinders
Professor Raymond Chan
Dr Nicolas Hart
Andi Agbejule
Research Collaborators
Dr Rahul Ladwa
Elizabeth Pinkham
Lee Jones
Jodie Nixon
Dr Bena Brown
Professor Steven McPhail
Distinguished Professor Patsy Yates
Laisa Teleni
Kerrie Doupain
Courtney Rawson
Jo Taylor
Princess Alexandra Research Foundation (PARF) - $100,000
Chief Investigators
Dr Rahul Ladwa
Professor Raymond Chan Elizabeth Pinkham
Lee Jones
Jodie Nixon
Dr Bena Brown
Professor Steven McPhail Distinguished Professor Patsy Yates
Commenced: 2021
Completion due: 2023
Cancer Council – Fatigue and Cancer
Ladwa R, Pinkham EP, Teleni L, et al. Telehealth cancer-related fatigue clinic model for cancer survivors: a pilot randomised controlled trial protocol (the T-CRF trial). BMJ Open. 2022 May 16;12(5):e059952. doi: 10.1136/bmjopen-2021-059952. PMID: 35577469.
Australia and New Zealand Clinical Trials Registry: ACTRN12620001334998
Queensland University of Technology
Cancer Council Queensland
Sturt Rd, Bedford Park
South Australia 5042
South Australia | Northern Territory
Global | Online
CRICOS Provider: 00114A TEQSA Provider ID: PRV12097 TEQSA category: Australian University
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